Immunosuppression in Viral Infections

Studies on Avian Viral Infections in Iran

Immunosuppression by viral N proteins

Arenaviruses and Coronaviruses (CoV) are enveloped RNA viruses. The nucleoproteins (N) of these viruses (termed nucleocapsid in CoV) play a key role in the formation of the viral ribonucleoprotein (RNP) complexes and in causing type I interferon (IFN) suppression. The primary function of the N proteins of CoV, such as the severe acute respiratory syndrome coronavirus (SARS-CoV), and of arenavir...

P-53: Chronic Viral Infections and Infertility in Male

Background: The most common sexually transmitted diseases and the economic and social health problem throughout the world. However, vaccine coverage and antibiotic therapy and the development of programs to prevent and control major causes of acute and chronic diseases, pregnancy complications and infertility remains. Acute and chronic systemic viral infections can lead to infertility and perma...

Viral infections in pregnancy.

The importance of protecting pregnant women from infection as well as from possible harmful effects of various medications and other noxious agents has received increasing attention in recent years. Much of the work related to viral diseases has been directed toward (1) identifying the agents that might be associated with fetal wastage and congenital malformations; (2) determining the risk to t...

Defensins in viral infections.

Defensins are antimicrobial peptides important to innate host defense. In addition to their direct antimicrobial effect, defensins modulate immune responses. Increasing evidence indicates that defensins exhibit complex functions by positively or negatively modulating infections of both enveloped and non-enveloped viruses. The effects of defensins on viral infections appear to be specific to the...